The duration of action for Tadalafil Femalefil, which contains tadalafil, typically lasts around 4 to 6 hours. However, some effects may be felt for longer, depending on individual metabolism and other factors. It's important to take Femalefil as directed by a healthcare provider, and the timing of when to take it before sexual activity can vary. If you have specific concerns or questions about its use, consulting a healthcare professional is advisable.